Introduction To Medical Imaging Physics Engineering And Clinical Applications Rar
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The University of Nebraska Medical Center (UNMC) lead team has been pioneering the development of low-cost, respiratory rate-independent ULF MRI for clinical diagnosis and therapy monitoring. Our first ULF MRI prototype has shown great promise in diagnosing various diseases of the central nervous system. This ULF MRI system exploits the combination of magnetic resonance imaging, electronic magnetic interference (EMI), signal detection, and medical physics engineering to form three key fundamental MRI contrasts: (1) fluid-attenuated inversion recovery (FLAIR)-like (T1-weighted), (2) T2-weighted (T2-weighted), and (3) diffusion-weighted imaging (DWI)8 (Fig. 1). These three fundamental contrasts can help diagnose various central nervous system (CNS) pathologies, including tumors and vascular diseases9,10. There are three major applications for our current ULF MRI development: a) obtaining high-resolution, high-contrast, high-contrast imaging of the CNS for diagnosis (Fig. 2), b) long-term imaging of the CNS for treatment monitoring (Fig. 3), and c) capturing high-resolution diffusion MRI data to provide detailed and multi-directional diffusion images of CNS tissues10-13.
Fig. 1T1W, T2W, and DWI contrasts obtained as a result of synthesizing FLAIR-like, T2-weighted, and DWI-like protocols, respectively, for the same subject. The three different contrasts in the same reconstructed 3D images (a) T1W, (b) T2W and (c) DWI 10. Figures a and c are from 3 T clinical MRI data (from donors/patients), and b is from a ULF prototype MRI data collected using 0.055 T permanent magnet. ULF-MRI is performed in less than 30 minutes using this scanner. Figures are reprinted from ref. 14 under a CC BY 4.0 license 10.
1386. He M, Xu J, Liao Y, Xu Y, Wang W, Zhang Y. Super-resolution medical image restoration based on review compression. In: Radiological Society of North America 2016 Annual Meeting. pp. 1127-1130. San Francisco; 2016. 25-28 April 2016. 7211a4ac4a